3-Methoxy-4-methyl-2-nitropyridine → 2-Pyridinamine,3-methoxy-4-methyl-(9CI)

HRID 1828529Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1828529
[CH3:1][O:2][C:3]1[C:4]([N+:10]([O-])=O)=[N:5][CH:6]=[CH:7][C:8]=1[CH3:9]>CO.[Pd]>[NH2:10][C:4]1[C:3]([O:2][CH3:1])=[C:8]([CH3:9])[CH:7]=[CH:6][N:5]=1

Komponenten

4

Edukt 1

HCID 149295773-Methoxy-4-methyl-2-nitropyridine2×

Produkt 1

HCID 220637652-Pyridinamine,3-methoxy-4-methyl-(9CI)Ausbeute 103,4 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

The 3-methoxy-4-methyl-2-nitropyridine (1 g) obtained in (A) was dissolved in methanol (50 ml), added with 5% Pd/C (200 mg), and stirred at a pressure of 40 psi for 2 hours under hydrogen atmosphere. After the catalyst was removed by filtration, the solvent was evaporated under reduced pressure to obtain the title compound (850 mg) as yellow oil.

Aufarbeitung

  1. customAfter the catalyst was removed by filtration
  2. customthe solvent was evaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-51b8d38c280b4a1b873c80a8120d7d35
Quelldatensatz
uspto-grants-2006_06
Patentnummer
US07056917B2

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