Bromide ion → 4-(4-Chloro-phenyl)-4-hydroxy-3,3-dimethyl-piperidine-1-carboxylic acid tert-butyl ester

Reaktionsgleichung

[Br-:17].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10]([CH3:15])([CH3:16])[C:11](=[O:14])[CH2:12][CH2:13]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[Cl:18][c:19]1[cH:20][cH:21][c:22]([Mg+:25])[cH:23][cH:24]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10]([CH3:15])([CH3:16])[C:11]([OH:14])([c:22]2[cH:21][cH:20][c:19]([Cl:18])[cH:24][cH:23]2)[CH2:12][CH2:13]1

Komponenten

Edukt 4

HCID 259Bromide ion

HCID 8028Tetrahydrofuran

HCID 22278899tert-Butyl 3,3-dimethyl-4-oxopiperidine-1-carboxylate

HCID 178507011HCID 178507011, Verbindung

Produkt 1

HCID 593412124-(4-Chloro-phenyl)-4-hydroxy-3,3-dimethyl-piperidine-1-carboxylic acid tert-butyl ester

Quellen und Nachweise

ORD-Eintrag: ord-b0e0ba13e7374e15a8defecf3827472b
Quelldatensatz: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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