Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Methylamine | HCID 6329 | — |
| Edukt | Phthalimidoamlodipine | HCID 9871958 | — |
| Produkt | Amlodipine | HCID 2162 | — |
Reaktionsschritte
Phthaloyl amlodipine (100 g, 0.18 M) was reacted with monomethyl amine (500 g, 40% solution) in denatured spirit at room temperature for 8 hrs, cooled to 0° C., filtered, washed with distilled water up to neutral pH and dried at 60-65° C. for 8 ills. Yield 58 g.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US06784297B2 |
|---|
| Quelldatensatz | uspto-grants-2004_08 |
|---|
| ORD ID | ord-0446c85fbae1475e863fd016fb81c07c |
|---|
| Quellennotiz | uspto-grants-2004_08 |
|---|
