Benzene → 2,6-Dibenzoylpyridine

HRID 1841513

Reaktionsgleichung

Reaktionsgleichung von HRID 1841513
[Cl-].[Cl-].[Cl-].[Al+3].Cl[C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([C:14](Cl)=[O:15])[N:9]=1)=[O:7].O.[CH:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([C:14](=[O:15])[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[N:9]=1)(=[O:7])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Komponenten

5

Edukt 4

HCID 241BenzeneHCID 962WaterHCID 773352,6-Pyridinedicarbonyl dichlorideHCID 6451240Aluminum(III) Chloride

Produkt 1

HCID 3166562,6-DibenzoylpyridineAusbeute 58 %

Reaktionsbedingungen

Temperatur
60 °C

Versuchsvorschrift

Aluminium trichloride (5.1 g, 3.18 mmol) was added to a suspension of 2,6-bis(chlorocarbonyl)pyridine (3.7 g, 18 mmol) in 200 ml of benzene. The reaction mixture was heated to 60° C. and kept at that temperature for 4 h and subsequently for 16 h at room temperature. The mixture was poured into water, the organic layer was separated and evaporated to dryness. The residue was dissolved in CH2Cl2 and filtered. Removal of CH2Cl2 in vacuum yielded 3.0 g (58%) of product.

Aufarbeitung

  1. customthe organic layer was separated
  2. customevaporated to dryness
  3. dissolutionThe residue was dissolved in CH2Cl2
  4. filtrationfiltered
  5. customRemoval of CH2Cl2 in vacuum

Quellen und Nachweise

ORD-Eintrag
ord-48fbbee0fd4c4da082c56e3bc44acdc8
Quelldatensatz
uspto-grants-2004_01
Patentnummer
US06683187B2

Verknüpfte Notizen

Wird geladen…