4-Amino-3-methyl-5-nitrophenol → 3,4-Diamino-5-methylphenol

HRID 1846455Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1846455
[NH2:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][C:5]([OH:11])=[CH:4][C:3]=1[CH3:12]>CO.[Pd]>[NH2:8][C:7]1[CH:6]=[C:5]([OH:11])[CH:4]=[C:3]([CH3:12])[C:2]=1[NH2:1]

Komponenten

4

Edukt 1

HCID 669782964-Amino-3-methyl-5-nitrophenol

Produkt 1

HCID 199076443,4-Diamino-5-methylphenol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

6.00 g (35.7 mmol) 4-amino-3-methyl-5-nitro-phenol in 200 mL MeOH was combined with 0.600 g palladium on charcoal (Pd/C 10%) and hydrogenated for 4 h under a hydrogen atmosphere of 60 psi at 50° C. The catalyst was removed by suction filtering, the filtrate was evaporated down and the residue was dried under HV.

Aufarbeitung

  1. customThe catalyst was removed by suction
  2. filtrationfiltering
  3. customthe filtrate was evaporated down
  4. customthe residue was dried under HV

Quellen und Nachweise

ORD-Eintrag
ord-b19c3f1f72114a598c1e9f7765e14387
Quelldatensatz
uspto-grants-2015_02
Patentnummer
US08952014B2

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