4-Amino-3-methyl-5-nitrophenol → 3,4-Diamino-5-methylphenol

HRID 1846488Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1846488
[NH2:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][C:5]([OH:11])=[CH:4][C:3]=1[CH3:12].[H][H]>CO.[Pd]>[NH2:8][C:7]1[CH:6]=[C:5]([OH:11])[CH:4]=[C:3]([CH3:12])[C:2]=1[NH2:1]

Komponenten

5

Edukt 2

HCID 669782964-Amino-3-methyl-5-nitrophenolHCID 178418361HCID 178418361, Verbindung2×

Produkt 1

HCID 199076443,4-Diamino-5-methylphenol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

2.00 g (11.06 mmol) 4-amino-3-methyl-5-nitrophenol were placed in 50 mL methanol and hydrogenated under a hydrogen atmosphere and with the addition of 1.00 g Pd/C (10%) at 50° C. and a hydrogen pressure of 5 bar until all the hydrogen had been taken up. The catalyst was filtered off and the filtrate was evaporated down i.vac.

Aufarbeitung

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated down i.vac

Quellen und Nachweise

ORD-Eintrag
ord-df0ec7a994e64585a5891541074e1775
Quelldatensatz
uspto-grants-2015_02
Patentnummer
US08952014B2

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