3,5-Diamino-1,2,4-triazole → HCID 178508251, Verbindung

HRID 1851217

Reaktionsgleichung

Reaktionsgleichung von HRID 1851217
[NH2:1][C:2]1[N:6]=[C:5]([NH2:7])[NH:4][N:3]=1.[C:8]1([CH:14]([C:20](OCC)=[O:21])[C:15](OCC)=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>C(N(CCCC)CCCC)CCC>[NH2:1][C:2]1[N:6]=[C:5]2[N:7]=[C:15]([OH:16])[C:14]([C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)=[C:20]([OH:21])[N:4]2[N:3]=1

Komponenten

4

Edukt 2

HCID 150783,5-Diamino-1,2,4-triazoleHCID 66514Diethyl phenylmalonate

Produkt 1

HCID 178508251HCID 178508251, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7622TributylamineLösungsmittel

Versuchsvorschrift

A solution of 9.0 g 3,5-diamino-1,2,4-triazole and 22.4 mL diethyl phenylmalonate in N,N-dibutylbutan-1-amine was heated under microwave irradiation to 180° C. for 8 h. The reaction mixture formed two layers after cooling to room temperature. The top layer was removed and the solvent of the lower layer was evaporated. The residue was treated with water and acidified with 5N HCl. The precipitated product was collected by filtration and dried. The crude product was used without further purification.

Aufarbeitung

  1. customThe reaction mixture formed two layers
  2. customThe top layer was removed
  3. customthe solvent of the lower layer was evaporated
  4. additionThe residue was treated with water
  5. filtrationThe precipitated product was collected by filtration
  6. customdried
  7. customThe crude product was used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-66d812d7ed2d46ae9b8c90c93a1783d1
Quelldatensatz
uspto-grants-2015_02
Patentnummer
US08957064B2

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