HCID 178498471, Verbindung → Methyl 5-amino-1H-pyrazole-3-carboxylate

HRID 1851230Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1851230
[N+:1]([C:4]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[NH:6][N:5]=1)([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[NH:6][N:5]=1

Komponenten

4

Edukt 1

HCID 178498471HCID 178498471, Verbindung

Produkt 1

HCID 18445864Methyl 5-amino-1H-pyrazole-3-carboxylate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

To 14.0 g methyl 3-nitro-1H-pyrazole-5-carboxylate in 200 mL methanol were added 1.2 g Pd/C (10% w/w). The mixture was stirred under H2-atmosphere at room temperature for 18 h. The mixture was filtered through Celite. The filtrate was concentrated and the crude product was used without further purification.

Aufarbeitung

  1. filtrationThe mixture was filtered through Celite
  2. concentrationThe filtrate was concentrated
  3. customthe crude product was used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-81fc562003f548ffa06cdd3904f5e467
Quelldatensatz
uspto-grants-2015_02
Patentnummer
US08957064B2

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