Water → N-acetyl-2-benzylsulfinylacetamide

HRID 1855757Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1855757
[C:1]([NH:4][C:5](=[O:15])[CH2:6][S:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=[O:3])[CH3:2].[OH2:16]>>[C:1]([NH:4][C:5](=[O:15])[CH2:6][S:7]([CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:16])(=[O:3])[CH3:2]

Komponenten

3

Edukt 2

HCID 962WaterHCID 12837900HCID 12837900, Verbindung

Produkt 1

HCID 20540297N-acetyl-2-benzylsulfinylacetamide

Versuchsvorschrift

To a solution of 0.011 mole of NaIO4 in 25 ml. of water which has been cooled to 5° C. is added 0.01 mole of N-acetyl-2-(benzylthio) acetamide. The reaction mixture is allowed to warm to room temperature and then stirred overnight and concentrated to dryness. Chromatography of the residue on 200 g. of silica gel eluting with ethyl acetate in hexane (25-75%) gives N-acetyl-2-benzylsulfinylacetamide.

Aufarbeitung

  1. concentrationconcentrated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-0b6c84c0f8b944da87f945eab402b1b5
Quelldatensatz
uspto-grants-1980_08
Patentnummer
US04216160

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