Benzene → (2-Chlorophenyl)diphenylmethanol

HRID 1855868Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1855868
[Cl-].[Al+3].[Cl-].[Cl-].[Cl:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12](Cl)(Cl)Cl.[OH2:16].[CH:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[Cl:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[OH:16]

Komponenten

5

Edukt 4

HCID 241Benzene2×HCID 962WaterHCID 16494Benzene, 1-chloro-2-(trichloromethyl)-HCID 6451240Aluminum(III) Chloride

Produkt 1

HCID 298659(2-Chlorophenyl)diphenylmethanol

Versuchsvorschrift

Into a flask, benzene (380 ml) was charged, and aluminum chloride (88 g) was suspended therein. A solution of o-chlorobenzotrichloride (138 g, 0.6 mole) in benzene (145 ml) was dropwise added thereto over 2 hours while keeping the temperature at 60° C. After the addition was completed, the mixture was refluxed for 2 hours. The reaction mixture was poured into water (600 ml), and the flask was washed with benzene (240 ml) and water (120 ml). The combined mixture was refluxed for 4 hours. The organic layer was separated, washed with water (400 ml), treated with charcoal (6 g) and filtered. Evaporation of the benzene filtrate gave 172.6 g of o-chlorophenyldiphenylmethanol as a crystalline mass. Yield, 97.7%. M.P., 88.5°-91.5° C.

Aufarbeitung

  1. customat 60° C
  2. additionAfter the addition
  3. temperaturethe mixture was refluxed for 2 hours
  4. washthe flask was washed with benzene (240 ml) and water (120 ml)
  5. temperatureThe combined mixture was refluxed for 4 hours
  6. customThe organic layer was separated
  7. washwashed with water (400 ml)
  8. additiontreated with charcoal (6 g)
  9. filtrationfiltered
  10. customEvaporation of the benzene filtrate

Quellen und Nachweise

ORD-Eintrag
ord-8847892dd2684a0f8b0f2a3659b96da3
Quelldatensatz
uspto-grants-1980_08
Patentnummer
US04216333

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