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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1857198Erstellt: 27. Oktober 2026

3-Hydroxybenzophenone → {3-[(6,7-Dimethoxy-4-quinolyl)oxy]phenyl}phenylmethanone

https://huagongshe.com/reaction/1857198

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-HydroxybenzophenoneHCID 83050—
Edukt4-Chloro-6,7-dimethoxyquinolineHCID 459610—
Produkt{3-[(6,7-Dimethoxy-4-quinolyl)oxy]phenyl}phenylmethanoneHCID 5390720565,3%

Reaktionsbedingungen

Temperatur170 °C

Reaktionsschritte

A mixture of 4-chloro-6,7-dimethoxyquinoline (112 mg) and commercially available 3-hydroxybenzophenone (297 mg) was stirred at 170° C. for 10 minutes, the reaction mixture was then purified by thin layer chromatography on silica gel eluting with hexane/acetone (2/1) to obtain 126 mg of the title compound (yield: 65%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06143764
Quelldatensatzuspto-grants-2000_11
ORD IDord-a2e9c24a256f4eb3a7ffd7bf2e26bd73
Quellennotizuspto-grants-2000_11