Water → HCID 18679841, Verbindung

HRID 1857541Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1857541
[CH2:1]([NH:5][CH3:6])[CH2:2][CH2:3][CH3:4].[Br:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][S:18](Cl)(=[O:20])=[O:19].O>C(Cl)Cl>[Br:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][S:18](=[O:20])(=[O:19])[N:5]([CH2:1][CH2:2][CH2:3][CH3:4])[CH3:6]

Komponenten

5

Edukt 3

HCID 962WaterHCID 8068N-MethylbutylamineHCID 1867984510-Bromodecanesulfonyl chloride

Produkt 1

HCID 18679841HCID 18679841, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

9.63 mmol of n-butylmethylamine is dissolved in 6 ml of absolute CH2Cl2. In a moisture-free environment, 1.85 mmol of 1-bromo-10-decanesulfonyl chloride is now slowly added in drops to 2.5 ml of CH2Cl2 while being cooled with ice. Then, it is stirred for another five hours at room temperature. The mixture is mixed with 10 ml of water, stirred thoroughly for a short time and the organic phase is separated. The aqueous phase is extracted with ether, and the combined organic phases are then washed with saturated NaCl solution and water. After drying on MgSO4, the solvent is removed in a rotary evaporator.

Aufarbeitung

  1. temperaturewhile being cooled with ice
  2. stirringstirred thoroughly for a short time
  3. customthe organic phase is separated
  4. extractionThe aqueous phase is extracted with ether
  5. washthe combined organic phases are then washed with saturated NaCl solution and water
  6. customAfter drying on MgSO4
  7. customthe solvent is removed in a rotary evaporator

Quellen und Nachweise

ORD-Eintrag
ord-a0b69944ae284a489ec8606ffb8f3283
Quelldatensatz
uspto-grants-2000_11
Patentnummer
US06147105

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