Oxalyl chloride → (3,5-Dimethylphenyl)acetyl chloride

HRID 1857625

Reaktionsgleichung

Reaktionsgleichung von HRID 1857625
[CH3:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([OH:12])=O)[CH:5]=[C:6]([CH3:8])[CH:7]=1.C(Cl)(=O)C([Cl:16])=O>CN(C)C=O>[CH3:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([Cl:16])=[O:12])[CH:5]=[C:6]([CH3:8])[CH:7]=1

Komponenten

4

Edukt 2

HCID 65578Oxalyl chlorideHCID 47494952-(3,5-Dimethylphenyl)acetic acid

Produkt 1

HCID 15895699(3,5-Dimethylphenyl)acetyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

To a solution of (3,5-dimethylphenyl)acetic acid (2.32 g in 25 mL dry methylene chloride) at 0° C. was added 0.055 mL N,N-dimethylformamide followed by the dropwise addition of 1.3 mL of oxalyl chloride. After 15 minutes the mixture was warmed to room temperature and stirred for an additional 2 hours. Removal of the solvents in vacuo provided the title compound which was used without purification.

Aufarbeitung

  1. customRemoval of the solvents in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-c29091bb72554589a55d44d3d513e5df
Quelldatensatz
uspto-grants-2000_11
Patentnummer
US06147088

Verknüpfte Notizen

Wird geladen…