Ethyl 3-(4-benzyloxyphenyl)-2-(4-methylphenoxy)propionate → Ethyl 3-(4-hydroxyphenyl)-2-(4-methylphenoxy)propionate

HRID 1860060Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1860060
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH:16]([O:22][C:23]2[CH:28]=[CH:27][C:26]([CH3:29])=[CH:25][CH:24]=2)[C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:11][CH:10]=1)C1C=CC=CC=1>[Pd]>[OH:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH:16]([O:22][C:23]2[CH:24]=[CH:25][C:26]([CH3:29])=[CH:27][CH:28]=2)[C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:11][CH:10]=1

Komponenten

3

Edukt 1

HCID 18625971Ethyl 3-(4-benzyloxyphenyl)-2-(4-methylphenoxy)propionate

Produkt 1

HCID 18626029Ethyl 3-(4-hydroxyphenyl)-2-(4-methylphenoxy)propionateAusbeute 103,9 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

In a similar manner to that described in Reference example 1(d), a reaction was carried out using ethyl 3-(4-benzyloxyphenyl)-2-(4-methylphenoxy)propionate (2.84 g), which is the product of Reference example 35(b), and palladium on carbon (284 mg) and the reaction mixture was treated to afford the desired compound (2.27 g) as a syrup.

Aufarbeitung

  1. additionthe reaction mixture was treated

Quellen und Nachweise

ORD-Eintrag
ord-4a4b0b236bc4468495f668469663b16c
Quelldatensatz
uspto-grants-2003_03
Patentnummer
US06528525B1

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