Hydrogen Bromide → 1-(Tetrahydro-2H-pyran-4-yl)ethanone
Reaktionsgleichung
[C:1]([C:4]1(C(OC)=O)[CH2:9][CH2:8][O:7][CH2:6][CH2:5]1)(=[O:3])[CH3:2].Br>>[C:1]([CH:4]1[CH2:9][CH2:8][O:7][CH2:6][CH2:5]1)(=[O:3])[CH3:2]Komponenten
3
Versuchsvorschrift
In a flask made of glass having an inner volume of 10 ml and equipped with a stirring device, a thermometer and a reflux condenser were charged 0.38 g (2.0 mmol) of 4-acetyl-4-methoxycarbonyltetrahydropyran with a purity of 99% and synthesized in the same manner as in Reference example 1 and 1.70 g (10 mmol) of 47% hydrobromic acid, and the mixture was reacted at 120° C. for 1 hour with stirring. After completion of the reaction, when the reaction mixture was analyzed by gas chromatography (Internal standard method), 0.17 g (Reaction yield: 65%) of 4-acetyltetrahydropyran was found to be formed.
Aufarbeitung
- customIn a flask made of glass
- customequipped with a stirring device
- customthe mixture was reacted at 120° C. for 1 hour
- customAfter completion of the reaction, when the reaction mixture
Quellen und Nachweise
- ORD-Eintrag
- ord-9f47635030934e0da52671bf25bc1c3e
- Quelldatensatz
- uspto-grants-2010_06
- Patentnummer
- US07741497B2
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