Oxaprozin → Butanedioic acid;bis(2-hydroxy-1,2-diphenylethanone)
Reaktionsgleichung
C1(C2N=[C:9]([CH2:18][CH2:19][C:20]([OH:22])=[O:21])[O:10]C=2C2C=CC=CC=2)C=CC=CC=1.[C:23]1([C:29]([CH:31]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[OH:32])=[O:30])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1.C1(=O)OC(=O)CC1>>[C:20]([OH:22])(=[O:21])[CH2:19][CH2:18][C:9]([OH:30])=[O:10].[C:23]1([C:29]([CH:31]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[OH:32])=[O:30])[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1.[C:23]1([C:29]([CH:31]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[OH:32])=[O:30])[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1Komponenten
4
Versuchsvorschrift
A process for the preparation of 4,5-diphenyloxazole-2-propanoic acid of formula I ##STR2## by esterification of benzoin with succinic anhydride to give benzoin hemisuccinate, and cyclization to (I) by direct addition of ammonium acetate or urea to the mixture containing the hemisuccinate,
Quellen und Nachweise
- ORD-Eintrag
- ord-cf112545ea7f4486bef9bbf657337f54