Beclomethasone Dipropionate → Beclomethasone

HRID 1875287Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1875287
CCC([O:5][CH2:6][C:7]([C@:9]1([O:32]C(CC)=O)[C@@:13]2([CH3:30])[CH2:14][C@H:15]([OH:29])[C@:16]3([Cl:28])[C@:26]4([CH3:27])[C:20](=[CH:21][C:22]([CH:24]=[CH:25]4)=[O:23])[CH2:19][CH2:18][C@H:17]3[C@@H:12]2[CH2:11][C@@H:10]1[CH3:31])=[O:8])=O>O.C(Cl)(Cl)Cl.CC(C)=O>[CH3:31][C@@H:10]1[C@:9]([OH:32])([C:7]([CH2:6][OH:5])=[O:8])[C@:13]2([CH3:30])[C@H:12]([C@H:17]3[C@:16]([Cl:28])([C@@H:15]([OH:29])[CH2:14]2)[C@:26]2([CH3:27])[C:20](=[CH:21][C:22]([CH:24]=[CH:25]2)=[O:23])[CH2:19][CH2:18]3)[CH2:11]1

Komponenten

5

Edukt 1

HCID 21700Beclomethasone Dipropionate2×

Produkt 1

HCID 20469Beclomethasone

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 180AcetoneLösungsmittelHCID 962WaterLösungsmittelHCID 6212ChloroformLösungsmittel

Versuchsvorschrift

Also preferably, the steroidal anti-inflammatory of the present formulations is beclomethasone dipropionate or its monohydrate. Beclomethasone dipropionate has the chemical name 9-chloro-11 b, 17,21-trih-ydroxy-16b-methylpregna-1,4-diene-3,20-doine 17,21-dipropionate. The compound may be a white powder with a molecular weight of 521.25; and is very slightly soluble in water (Physicians' Desk Reference.RTM), very soluble in chloroform, and freely soluble in acetone and in alcohol.

Quellen und Nachweise

ORD-Eintrag
ord-5b424f4b284646bc83b6bc4197c8fef3
Quelldatensatz
uspto-grants-2012_11
Patentnummer
US08309061B2

Notizen zur Reaktion

Wird geladen…