Thionyl Chloride → 1-(1-Chloroethyl)naphthalene

HRID 1886527

Reaktionsgleichung

Reaktionsgleichung von HRID 1886527
[C:1]1([CH:11](O)[CH3:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:16])=O>C1(C)C=CC=CC=1>[C:1]1([CH:11]([Cl:16])[CH3:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 980301-(1-Naphthyl)ethanol

Produkt 1

HCID 132442811-(1-Chloroethyl)naphthalene

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

A solution of 1-(1-naphthalyl)ethanol (6.34 g, 38.8 mmol) and thionyl chloride (5.37 ml, 73.6 mmol) in 65 ml of toluene was refluxed for 4 hours. The reaction mixture was evaporated to give the residue as an oil. The residue was dissolved in 150 ml of ethyl acetate, washed successively with 50 ml of water, 50 ml of saturated sodium bicarbonate and 50 ml of brine, and dried over sodium sulfate. The solvent was removed in vacuo to give 3(6.83 g, 97%) as an oil.

Aufarbeitung

  1. customThe reaction mixture was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-aeeee3d783ad454c8ab37aa78190e494
Quelldatensatz
uspto-grants-1992_09
Patentnummer
US05151526

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