Formic Acid → HCID 178507597, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[N:7]=[C:6]2[S:8]C(N)=[N:10][C:5]2=[CH:4][CH:3]=1.S([O-])([O-])=O.[Na+].[Na+].C(O)=O>[OH-].[Na+]>[NH2:10][C:5]1[C:6]([SH:8])=[N:7][C:2]([Cl:1])=[CH:3][CH:4]=1Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
5-Chlorothiazolo[5,4-b]pyridin-2-amine (Q-2) (19 g, 103 mmol) containing sodium sulfite (2 g) was refluxed in 20% aqueous sodium hydroxide solution (150 mL) overnight. The solids were completely dissolved after 1 h, then cooled to room temperature. The solution was neutralized with formic acid. A precipitate was collected by filtration as the title compound (16.4 g).
Aufarbeitung
- dissolutionThe solids were completely dissolved after 1 h
- filtrationA precipitate was collected by filtration as the title compound (16.4 g)
Quellen und Nachweise
- ORD-Eintrag
- ord-f2b7cc04f9db4202b460d5cfef14b90a
- Quelldatensatz
- uspto-grants-2013_08
- Patentnummer
- US08507487B2
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