Acetic Anhydride → 3-Acetylamino-1-benzyl-4-methylpyrrolidine
Reaktionsgleichung
[NH2:1][CH:2]1[CH:6]([CH3:7])[CH2:5][N:4]([CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:3]1.[C:15](OC(=O)C)(=[O:17])[CH3:16]>>[C:15]([NH:1][CH:2]1[CH:6]([CH3:7])[CH2:5][N:4]([CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:3]1)(=[O:17])[CH3:16]Komponenten
3
Versuchsvorschrift
3-Amino-1-benzyl-4-methylpyrrolidine (Japanese Laid-Open Patent Publication No. 22699/1980) was allowed to react with acetic anhydride to give 3-acetylamino-1-benzyl-4-methylpyrrolidine; IR 3300, 1650 cm-1. This compound was hydrogenated catalytically in the presence of 5% palladium-carbon to give 3-acetylamino-4-methylpyrrolidine as an oil.
Quellen und Nachweise
- ORD-Eintrag
- ord-708c2b3e03a4469e871171616fa90154
- Quelldatensatz
- uspto-grants-1987_03
- Patentnummer
- US04649144