Sulfuryl chloride → [(Chlorocarbonyl)oxy]methyl 2-methylpropanoate
Reaktionsgleichung
[CH3:1][CH:2]([CH3:13])[C:3]([O:5][CH2:6][O:7][C:8](SCC)=[O:9])=[O:4].S(Cl)([Cl:17])(=O)=O>>[CH3:1][CH:2]([CH3:13])[C:3]([O:5][CH2:6][O:7][C:8]([Cl:17])=[O:9])=[O:4]Komponenten
3
Versuchsvorschrift
The compound (400 mg) obtained in Step 2 of this Example was cooled to −30° C. Sulfuryl chloride (159 μL) was added thereto, and the mixture was stirred at the same temperature for 20 minutes. The mixture was in turn stirred for 20 minutes in an ice bath and further at room temperature for 1 hour. The solvent was distilled off under reduced pressure, and the residue was dried to obtain a crude product of the title compound.
Aufarbeitung
- customwas cooled to −30° C
- stirringstirred for 20 minutes in an ice bath and further at room temperature for 1 hour
- distillationThe solvent was distilled off under reduced pressure
- customthe residue was dried
Quellen und Nachweise
- ORD-Eintrag
- ord-c58152f509424c4793a0f1ef193ef4f6
- Quelldatensatz
- uspto-grants-2013_12
- Patentnummer
- US08609710B2
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