Acetate → ethyl [(trans-4-{7-butyl-6-[(2'-cyano-2-fluorobiphenyl-4-yl)methyl]-5-oxopyrazolo[1,5-a]pyrimidin-4(5H)-yl}cyclohexyl)oxy]acetate

HRID 192487

Reaktionsgleichung

Reaktionsgleichung von HRID 192487
[C:60]([O-:61])(=[O:62])[CH3:63].[C:65]([O-:66])(=[O:67])[CH3:68].[C:69]([O-:70])(=[O:71])[CH3:72].[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[c:6]([CH2:22][c:23]2[cH:24][c:25]([F:37])[c:26](-[c:29]3[c:30]([C:35]#[N:36])[cH:31][cH:32][cH:33][cH:34]3)[cH:27][cH:28]2)[c:7](=[O:21])[n:8]([CH:14]2[CH2:15][CH2:16][CH:17]([OH:20])[CH2:18][CH2:19]2)[c:9]2[n:10]1[n:11][cH:12][cH:13]2.[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[CH3:53][c:54]1[cH:55][cH:56][cH:57][cH:58][cH:59]1.[N+:38](=[N-:39])=[CH:40][C:41](=[O:42])[O:43][CH2:44][CH3:45].[OH2:52].[Rh+3:64]>>[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[c:6]([CH2:22][c:23]2[cH:24][c:25]([F:37])[c:26](-[c:29]3[c:30]([C:35]#[N:36])[cH:31][cH:32][cH:33][cH:34]3)[cH:27][cH:28]2)[c:7](=[O:21])[n:8]([CH:14]2[CH2:15][CH2:16][CH:17]([O:20][CH2:40][C:41](=[O:42])[O:43][CH2:44][CH3:45])[CH2:18][CH2:19]2)[c:9]2[n:10]1[n:11][cH:12][cH:13]2

Komponenten

8

Edukt 7

HCID 175Acetate3×HCID 962WaterHCID 1140TolueneHCID 8857Ethyl AcetateHCID 12192Ethyl diazoacetateHCID 167511Rhodium(3+)HCID 670101494'-{[7-Butyl-4-(trans-4-hydroxycyclohexyl)-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-6-yl]methyl}-2'-fluorobiphenyl-2-carbonitrile

Produkt 1

HCID 86644069ethyl [(trans-4-{7-butyl-6-[(2'-cyano-2-fluorobiphenyl-4-yl)methyl]-5-oxopyrazolo[1,5-a]pyrimidin-4(5H)-yl}cyclohexyl)oxy]acetate

Quellen und Nachweise

ORD-Eintrag
ord-611b320f21924d4e81ca3ca66c509426
Quelldatensatz
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

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