Reaktionsgleichung
C([O:24][CH:25]([C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=1[Br:33])[CH3:26])(=O)CCCCCCCCCCCCCCCCCCCCC>O>[Br:33][C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=1[C@@H:25]([OH:24])[CH3:26]Komponenten
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Interesterification was carried out by using 3 g of Lipase QL, 50 g of (R,S)-1-(2-bromophenyl)ethanol, and 150 g of tribehen at 120° C. for 20 hours in the same manner as in Example 12. The water content of the reaction system was 0.01% by weight, and 90% of the lipase particles had a particle size of 30 to 50 μm. Gas chromatography of the reaction mixture revealed that 44 mol % of (R,S)-1-(2-bromophenyl)ethanol had been converted to 1-(2-bromophenyl)ethyl behenate. The reaction mixture was treated in the same manner as in Example 12, and the filtrate was subjected to simple distillation at 110° C. and 5 mmHg to recover unreacted (S)-(-)-1-(2-bromophenyl)ethanol (yield: 88%; chemical purity: 99.9%; optical purity: 99% ee or higher).
Aufarbeitung
- customat 120° C.
- customfor 20 hours
- additionThe reaction mixture was treated in the same manner as in Example 12
- distillationthe filtrate was subjected to simple distillation at 110° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-cc88f2f51df940b8936dbb7e7a8ad1f1
- Quelldatensatz
- uspto-grants-1997_12
- Patentnummer
- US05696299
Verknüpfte Notizen
Wird geladen…