N-Benzyl-N-nitroso-p-toluenesulfonamide → Benzene, (diazomethyl)-

HRID 1941465

Reaktionsgleichung

Reaktionsgleichung von HRID 1941465
C[O-].[Na+].[N:4]([N:6]([CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)S(C1C=CC(C)=CC=1)(=O)=O)=O>COC(C)(C)C>[C:18]1([CH:17]=[N+:6]=[N-:4])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Komponenten

4

Edukt 2

HCID 4118076N-Benzyl-N-nitroso-p-toluenesulfonamideHCID 10942334Sodium Methoxide

Produkt 1

HCID 136601Benzene, (diazomethyl)-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 15413tert-Butyl methyl etherLösungsmittel

Versuchsvorschrift

To a solution of sodium methoxide (1.2 equivalent, 4.0 ml of 1M solution in methanol) in tert-butyl methyl ether (12 ml) was added N-nitroso-N-benzyl-p-toluenesulphonamide (966 mg, 3.34 mmol) in small portions at room temperature. After the addition was finished the reaction mixture was refluxed for 15-30 minutes. The reaction mixture was cooled and washed with water (3×12 ml). The etheral solution of phenyldiazomethane was dried over sodium sulphate for 30 minutes.

Aufarbeitung

  1. additionAfter the addition
  2. temperaturewas refluxed for 15-30 minutes
  3. temperatureThe reaction mixture was cooled
  4. washwashed with water (3×12 ml)
  5. dry with materialThe etheral solution of phenyldiazomethane was dried over sodium sulphate for 30 minutes

Quellen und Nachweise

ORD-Eintrag
ord-f3b122735a3948e1ac9bbdc5b88da32f
Quelldatensatz
uspto-grants-1997_12
Patentnummer
US05703246

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