2-Oxazolidinone → rac-3-[1-(5-Phenylethynyl-pyridin-2-yl)-ethyl]-oxazolidin-2-one
Reaktionsgleichung
[C:1]1([C:7]#[C:8][C:9]2[CH:10]=[CH:11][C:12]([CH:15](O)[CH3:16])=[N:13][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[O:18]1[CH2:22][CH2:21][NH:20][C:19]1=[O:23]>>[C:1]1([C:7]#[C:8][C:9]2[CH:10]=[CH:11][C:12]([CH:15]([N:20]3[CH2:21][CH2:22][O:18][C:19]3=[O:23])[CH3:16])=[N:13][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1Komponenten
3
Versuchsvorschrift
The title compound, white solid, MS: m/e=293.1 (M+H+), can be prepared in accordance with the general method of example 31, step 2 from rac-1-(5-phenylethynyl-pyridin-2-yl)-ethanol (example 42, step 1) and oxazolidin-2-one.
Quellen und Nachweise
- ORD-Eintrag
- ord-c4cc2e0a5f1d498889f1791e61b9c41d
- Quelldatensatz
- uspto-grants-2013_03
- Patentnummer
- US08389536B2