HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-cyclopropyl-1H-1,3-benzodiazole → ethyl 2-(4-((2-(2-cyclopropyl-1H-benzo[d]imidazol-1-yl)-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperazin-1-yl)-2-methylpropanoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-cyclopropyl-1H-1,3-benzodiazole | HCID 1084419 | — |
| Edukt | ethyl 2-(4-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperazin-1-yl)-2-methylpropanoate | HCID 86648267 | — |
| Produkt | ethyl 2-(4-((2-(2-cyclopropyl-1H-benzo[d]imidazol-1-yl)-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperazin-1-yl)-2-methylpropanoate | HCID 59606061 | — |
Reaktionsschritte
Following General Procedure I for Buchwald coupling, 2-cyclopropylbenzimidazole and ethyl 2-(4-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperazin-1-yl)-2-methylpropanoate were reacted to give 500. LCMS m/z: 588.4 (MH+)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08394796B2 |
| Quelldatensatz | uspto-grants-2013_03 |
| ORD ID | ord-627e16e5914144bfbfaa5111362f764c |
| Quellennotiz | uspto-grants-2013_03 |