Phosphorus pentachloride → 2-Chloro-1-methyl-5-nitro-1H-benzimidazole

HRID 1953261Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1953261
P(Cl)(Cl)(Cl)(Cl)[Cl:2].[N+:7]([C:10]1[CH:20]=[CH:19][C:13]2[N:14]([CH3:18])[C:15](=O)[NH:16][C:12]=2[CH:11]=1)([O-:9])=[O:8]>P(Cl)(Cl)(Cl)=O>[N+:7]([C:10]1[CH:20]=[CH:19][C:13]2[N:14]([CH3:18])[C:15]([Cl:2])=[N:16][C:12]=2[CH:11]=1)([O-:9])=[O:8]

Komponenten

4

Edukt 2

HCID 24819Phosphorus pentachlorideHCID 6063051-Methyl-5-nitro-1,3-dihydro-2H-benzimidazol-2-one

Produkt 1

HCID 108223912-Chloro-1-methyl-5-nitro-1H-benzimidazole

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 24813Phosphorus oxychlorideLösungsmittel

Reaktionsbedingungen

Temperatur
125 °C

Versuchsvorschrift

2.1 g (0.01 mol) of phosphorus pentachloride are dissolved in 2.5 ml phosphorus oxychloride and after the addition of 1.9 g (0.01 mol) of 5-nitro-1-methyl-benzimidazol-2-one the mixture is stirred for two hours at 125° C. The solvent is evaporated off, the residue is poured onto ice water and neutralised with ammonia. The precipitate formed is suction filtered and dried.

Aufarbeitung

  1. customThe solvent is evaporated off
  2. additionthe residue is poured onto ice water and neutralised with ammonia
  3. customThe precipitate formed
  4. filtrationfiltered
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-34226644c38e457ebf81005291fb39db
Quelldatensatz
uspto-grants-2000_09
Patentnummer
US06114532

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