Benzoyl Peroxide → 3-(4-(Bromomethyl)phenyl)thiophene

HRID 1957019Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1957019
[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH3:12])=[CH:8][CH:7]=2)=[CH:2]1.[Br:13]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH2:12][Br:13])=[CH:8][CH:7]=2)=[CH:2]1

Komponenten

5

Edukt 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 41303473-(4-Methylphenyl)thiophene

Produkt 1

HCID 137735383-(4-(Bromomethyl)phenyl)thiophene

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 5943Carbon TetrachlorideLösungsmittel

Versuchsvorschrift

To a solution of 4-(3-thienyl)toluene (3.56 g, 20.5 mmol) in carbon tetrachloride (100 ml) is added N-bromosuccinimide (3.64 g, 20.5 mol) and benzoyl peroxide (80 mg, 3.3 mmol). The reaction mixture is heated at reflux for 24 hrs. and concentrated in vacuo. The reaction mixture is recrystallized from ethanol to afford 4-(3-thienyl)benzyl bromide.

Aufarbeitung

  1. temperatureThe reaction mixture is heated
  2. temperatureat reflux for 24 hrs
  3. concentrationand concentrated in vacuo
  4. customThe reaction mixture is recrystallized from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-ef8bed6f4a65437fb5f42700a13c9323
Quelldatensatz
uspto-grants-1998_07
Patentnummer
US05780498

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