Acetate → tert-butyl (3RS,4RS)-4-[4-(2-ethoxycarbonyl-vinyl)-phenyl]-3-hydroxy-piperidine-1-carboxylate

HRID 195816

Reaktionsgleichung

Reaktionsgleichung von HRID 195816
[Br:23][c:24]1[cH:25][cH:26][c:27]([CH:30]2[CH:31]([OH:43])[CH2:32][N:33]([C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:34][CH2:35]2)[cH:28][cH:29]1.[C:44]([CH:45]=[CH2:46])(=[O:47])[O:48][CH2:49][CH3:50].[CH3:52][C:53](=[O:54])[O-:55].[Na+:51].[O-:62][C:63]([CH3:64])=[O:65].[O-:66][C:67]([CH3:68])=[O:69].[O:56]=[CH:57][N:58]([CH3:59])[CH3:60].[Pd+2:61].[c:1]1([CH3:2])[cH:3][cH:4][cH:5][cH:6][c:7]1[P:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][c:14]1[CH3:15])[c:16]1[cH:17][cH:18][cH:19][cH:20][c:21]1[CH3:22]>>[c:24]1([CH:46]=[CH:45][C:44](=[O:47])[O:48][CH2:49][CH3:50])[cH:25][cH:26][c:27]([CH:30]2[CH:31]([OH:43])[CH2:32][N:33]([C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:34][CH2:35]2)[cH:28][cH:29]1

Komponenten

8

Edukt 7

HCID 175Acetate3×HCID 923Sodium ionHCID 6228DimethylformamideHCID 8821Ethyl AcrylateHCID 80271Tri-o-tolylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 54537313tert-butyl (3RS,4RS)-4-(4-bromophenyl)-3-hydroxy-piperidine-1-carboxylate

Produkt 1

HCID 86604399tert-butyl (3RS,4RS)-4-[4-(2-ethoxycarbonyl-vinyl)-phenyl]-3-hydroxy-piperidine-1-carboxylate

Quellen und Nachweise

ORD-Eintrag
ord-35fa4b9e89b34ad791fa614095630736
Quelldatensatz
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Verknüpfte Notizen

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