2-[(Benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane → 5,8-Dioxaspiro[3.4]octane-2-methanol

HRID 1966814Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1966814
C([O:8][CH2:9][CH:10]1[CH2:13][C:12]2([O:17][CH2:16][CH2:15][O:14]2)[CH2:11]1)C1C=CC=CC=1>CO.[Pd]>[CH2:11]1[C:12]2([O:17][CH2:16][CH2:15][O:14]2)[CH2:13][CH:10]1[CH2:9][OH:8]

Komponenten

4

Edukt 1

HCID 120735822-[(Benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane

Produkt 1

HCID 120735835,8-Dioxaspiro[3.4]octane-2-methanol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

Palladium/carbon (10%) was added to a solution of 2-[(benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane (22.0 gm, 94.0 mmol) (step c) in methanol and the mixture was stirred at room temperature under hydrogen balloon for about 4 hours. It was filtered through celite bed and residue was washed with methanol. The combined filtrate was concentrated under reduced pressure.

Aufarbeitung

  1. filtrationIt was filtered through celite bed and residue
  2. washwas washed with methanol
  3. concentrationThe combined filtrate was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-7de2674c31184f9e89e447183164d3c9
Quelldatensatz
uspto-grants-2013_04
Patentnummer
US08420666B2

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