Cesium carbonate → N-(4-(7-(3-(1-hydroxycyclopropyl)propoxy)-6-methoxyquinolin-4-yloxy)-3-fluorophenyl)-N-phenylcyclopropane-1,1-dicarboxamide

Reaktionsgleichung

[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([O:12][C:13]3[CH:18]=[CH:17][C:16]([N:19]([C:28]4[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=4)[C:20]([C:22]4([C:25]([NH2:27])=[O:26])[CH2:24][CH2:23]4)=[O:21])=[CH:15][C:14]=3[F:34])=[CH:7][CH:8]=[N:9]2)=[CH:4][C:3]=1[O:35][CH3:36].CS(O[CH2:42][CH2:43][CH2:44][C:45]1([OH:48])[CH2:47][CH2:46]1)(=O)=O.C([O-])([O-])=O.[Cs+].[Cs+]>CC(N(C)C)=O>[OH:48][C:45]1([CH2:44][CH2:43][CH2:42][O:1][C:2]2[CH:11]=[C:10]3[C:5]([C:6]([O:12][C:13]4[CH:18]=[CH:17][C:16]([N:19]([C:28]5[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=5)[C:20]([C:22]5([C:25]([NH2:27])=[O:26])[CH2:24][CH2:23]5)=[O:21])=[CH:15][C:14]=4[F:34])=[CH:7][CH:8]=[N:9]3)=[CH:4][C:3]=2[O:35][CH3:36])[CH2:47][CH2:46]1