Hydroxyamine hydrochloride → HCID 86611440, Verbindung

Reaktionsgleichung

Cl.[NH2:2][OH:3].[CH3:4][O:5][C:6]1[CH:21]=[C:20]([O:22][CH3:23])[CH:19]=[CH:18][C:7]=1[C:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[O:16][CH3:17])=O>C(O)C.N1C=CC=CC=1>[CH3:4][O:5][C:6]1[CH:21]=[C:20]([O:22][CH3:23])[CH:19]=[CH:18][C:7]=1[C:8](=[N:2][OH:3])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[O:16][CH3:17]

Komponenten

Versuchsvorschrift

Hydroxylamine hydrochloride (4.98 g, 71.7 mmol) is added to a solution of 2,2′,4-tri-methoxybenzophenone (J. Org. Chem. 1996, 61, 6326; 6.5 g, 23.9 mmol) in ethanol (50 ml) and pyridine (10 ml). The mixture is heated at reflux for 2 hours and the solvent evaporated. The residue is partitioned between dichloromethane and 2 M aqueous HCl and the organic phase is washed with water, brine, dried (MgSO4) and evaporated to afford the title compound.