Water → Sulfate Ion

HRID 1974322

Reaktionsgleichung

Reaktionsgleichung von HRID 1974322
[CH3:1][CH:2]([NH:32][CH3:33])[CH:3]1[O:8][CH:7]([O:9][CH:10]2[CH:15]([OH:16])[CH:14]([O:17][CH:18]3[O:23][CH2:22][C:21]([OH:25])([CH3:24])[CH:20]([NH:26][CH3:27])[CH:19]3[OH:28])[CH:13]([NH2:29])[CH2:12][CH:11]2[NH2:30])[CH:6]([NH2:31])[CH2:5][CH2:4]1.O.[S:35](=[O:39])(=[O:38])([OH:37])[OH:36]>CO>[CH3:1][CH:2]([NH:32][CH3:33])[CH:3]1[O:8][CH:7]([O:9][CH:10]2[CH:15]([OH:16])[CH:14]([O:17][CH:18]3[O:23][CH2:22][C:21]([OH:25])([CH3:24])[CH:20]([NH:26][CH3:27])[CH:19]3[OH:28])[CH:13]([NH2:29])[CH2:12][CH:11]2[NH2:30])[CH:6]([NH2:31])[CH2:5][CH2:4]1.[S:35]([O-:39])([O-:38])(=[O:37])=[O:36]

Komponenten

6

Edukt 3

HCID 962WaterHCID 1118Sulfuric AcidHCID 3467Gentamicin

Produkt 2

HCID 1117Sulfate IonHCID 3467Gentamicin

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

Dissolve 5.0 gm. of 5-epigentamicin C1 in 25 ml. of water and adjust the pH of the solution to 4.5 with 1 N sulfuric acid. Pour into about 300 ml. of methanol with vigorous agitation, continue the agitation for about 10-20 minutes and filter. Wash the precipitate with methanol and dry at about 60° C in vacuo to obtain 5-epigentamicin C1 sulfate.

Aufarbeitung

  1. dissolutionDissolve 5.0 gm
  2. additionPour into about 300 ml
  3. customfor about 10-20 minutes
  4. filtrationfilter
  5. washWash the precipitate with methanol
  6. customdry at about 60° C in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-4684516e1a0a4c46b4b043c1cc2872ae
Quelldatensatz
uspto-grants-1976_12
Patentnummer
US04000261

Verknüpfte Notizen

Wird geladen…