Potassium Carbonate → 2,9-Diazatricyclo[5.3.0.0,2,5]decane

HRID 1975014Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1975014
[N:1]12[CH2:10][CH2:9][CH:8]1[CH2:7][CH:6]1[CH:2]2[CH2:3][N:4](C(OCC)=O)[CH2:5]1.C(=O)([O-])[O-].[K+].[K+]>O>[N:1]12[CH2:10][CH2:9][CH:8]1[CH2:7][CH:6]1[CH:2]2[CH2:3][NH:4][CH2:5]1

Komponenten

4

Edukt 2

HCID 11430Potassium CarbonateHCID 54190177Ethyl 1,4-diazatricyclo [6.2.0.02,6]decane-4-carboxylate

Produkt 1

HCID 162289032,9-Diazatricyclo[5.3.0.0,2,5]decane

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

13.7 g (65.1 mmol) of ethyl 1,4-diazatricyclo[6.2.0.02,6 ]decane-4-carboxylate together with 42 g of Ba(OH)2 ×8H2O are refluxed overnight in 150 ml of water. Potassium carbonate is added, barium carbonate is filtered off with suction, and the filtrate is extracted ten times using 100 ml portions of chloroform. The extracts are dried over potassium carbonate and concentrated, and the residue is distilled.

Aufarbeitung

  1. filtrationbarium carbonate is filtered off with suction
  2. extractionthe filtrate is extracted ten times
  3. dry with materialThe extracts are dried over potassium carbonate
  4. concentrationconcentrated
  5. distillationthe residue is distilled

Quellen und Nachweise

ORD-Eintrag
ord-52b3a3bafcc645e28824fe18c7fcb92c
Quelldatensatz
uspto-grants-1994_02
Patentnummer
US05284855

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