Iodoethane → HCID 178477485, Verbindung

HRID 1975902Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1975902
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([NH:14][C:15]([NH2:17])=[S:16])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[I:18][CH2:19][CH3:20]>CC(C)=O>[IH:18].[CH2:19]([S:16][C:15](=[NH:17])[NH:14][C:11]1[CH:12]=[CH:13][C:8]([O:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:9][CH:10]=1)[CH3:20]

Komponenten

4

Edukt 2

HCID 6340IodoethaneHCID 27603494-Phenoxyphenylthiourea

Produkt 1

HCID 178477485HCID 178477485, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

To a stirred solution of 1-(4-phenoxyphenyl)-2-thiourea (2.00 g, 8.19 mmol) in acetone (20 ml) was added iodoethane (7.61 g, 48.7 mmol). The mixture was heated to reflux for three hours, cooled to room temperature and concentrated at reduced pressure. The resulting viscous oil was crystallized from acetone-pentane to afford S-ethyl-N-(4-phenoxyphenyl)isothiourea hydroiodide as a beige solid. Mp=140-143° C.

Aufarbeitung

  1. temperatureThe mixture was heated
  2. temperatureto reflux for three hours
  3. concentrationconcentrated at reduced pressure
  4. customThe resulting viscous oil was crystallized from acetone-pentane

Quellen und Nachweise

ORD-Eintrag
ord-bc9406f2ad1d4b459e5b1ff78e25e25c
Quelldatensatz
uspto-grants-2001_05
Patentnummer
US06225305B1

Notizen zur Reaktion

Wird geladen…