Trifluoroacetic anhydride → HCID 22880382, Verbindung

HRID 1978087Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1978087
[C:1]([C@H:4]([CH2:10][CH:11]([CH3:13])[CH3:12])[C@H:5]([OH:9])[C:6]([OH:8])=[O:7])([OH:3])=[O:2].F[C:15](F)(F)C(OC(=O)C(F)(F)F)=O>>[C:1]([C@H:4]([CH2:10][CH:11]([CH3:13])[CH3:12])[C@H:5]([OH:9])[C:6]([O:8][CH3:15])=[O:7])([OH:3])=[O:2]

Komponenten

3

Edukt 2

HCID 9845Trifluoroacetic anhydrideHCID 10845347Disodium (2S,3R)-2-hydroxy-3-isobutylsuccinate

Produkt 1

HCID 22880382HCID 22880382, Verbindung

Versuchsvorschrift

4.48 g of 3(R)-carboxy-2(S)-hydroxy-5-methylhexanoic acid were stirred under nitrogen in 10 ml of trifluoroacetic anhydride for 1.5 hours. The solvent was evaporated and the residue was dissolved in 20 ml of dry methanol and stirred overnight at room temperature. The solvent was evaporated to give 5.3 g of methyl 3(R)-carboxy-2(S)-hydroxy-5-methylhexanoate in the form of an orange oil.

Aufarbeitung

  1. customThe solvent was evaporated
  2. dissolutionthe residue was dissolved in 20 ml of dry methanol
  3. customThe solvent was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-6efa1773777f44bab4707db4573dc354
Quelldatensatz
uspto-grants-2001_05
Patentnummer
US06235787B1

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