Carbonyl fluoride → 4-Chloro-3-(trifluoromethyl)phenyl carbamic fluoride

HRID 1979629

Reaktionsgleichung

Reaktionsgleichung von HRID 1979629
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]=[C:9]=[O:10])=[CH:4][C:3]=1[C:11]([F:14])([F:13])[F:12].F.C(F)([F:18])=O>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([F:18])=[O:10])=[CH:4][C:3]=1[C:11]([F:12])([F:13])[F:14]

Komponenten

4

Edukt 3

HCID 9623Carbonyl fluorideHCID 14917Hydrofluoric Acid2×HCID 27332651-Chloro-4-isocyanato-2-(trifluoromethyl) benzene

Produkt 1

HCID 204396094-Chloro-3-(trifluoromethyl)phenyl carbamic fluoride

Reaktionsbedingungen

Temperatur
24 °C

Versuchsvorschrift

4-Chloro-3-(trifluoromethyl)phenyl carbamic fluoride was prepared in situ by the reaction of 221 parts of 4-chloro-3-(trifluoromethyl)isocyanatobenzene and 450 parts of hydrogen fluoride added over a period of 15-20 minutes at about 4° C. The reaction mixture was then sealed in a polytetrafluoroethylene reactor, heated to about 24° C. and maintained thereat, with agitation, for about 96 hours. The reactor was then opened to atmospheric pressure and most of the hydrogen fluoride and carbonyl fluoride gases removed. Analysis of the remaining organic product by gas chromatographic techniques, using n-heptadecane as an internal standard indicated a yield of 77 parts of 4-chloro-3-(trifluoromethyl)benzenamine.

Aufarbeitung

  1. additionadded over a period of 15-20 minutes at about 4° C
  2. customThe reaction mixture was then sealed in a polytetrafluoroethylene reactor
  3. temperaturemaintained
  4. customremoved

Quellen und Nachweise

ORD-Eintrag
ord-f2907788c7834689b5bc788e03074260
Quelldatensatz
uspto-grants-1984_11
Patentnummer
US04481370

Verknüpfte Notizen

Wird geladen…