Acetone → HCID 12962350, Verbindung

HRID 1979879Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1979879
[C:1]1([CH:7]2[NH:11][CH2:10][CH2:9][S:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CC(C)=O.[Cl:16][CH:17]([Cl:21])[C:18](Cl)=[O:19]>O>[C:1]1([CH:7]2[N:11]([C:18](=[O:19])[CH:17]([Cl:21])[Cl:16])[CH2:10][CH2:9][S:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Komponenten

5

Edukt 3

HCID 180AcetoneHCID 6593Dichloroacetyl chlorideHCID 207062-Phenylthiazolidine

Produkt 1

HCID 12962350HCID 12962350, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

Five (5) grams of 2-phenyl thiazolidine was dissolved in 50 ml. of acetone, 3.1 g. of thiethylamine was added and the mixture stirred in a room temperature water bath, while 4.4 g. of dichloroacetyl chloride was added dropwise. The mixture was allowed to stand for about 30 minutes and then poured into water, extracted with methylene chloride, separated, dried over magnesium sulfate, and the solvent stripped under vacuum. There was obtained a yield of 7.3 g. of an oil, the title compound, ND30 =1.5836.

Aufarbeitung

  1. additionof thiethylamine was added
  2. extractionextracted with methylene chloride
  3. customseparated
  4. dry with materialdried over magnesium sulfate
  5. customThere was obtained a yield of 7.3 g

Quellen und Nachweise

ORD-Eintrag
ord-9e04a2b60641407ca64955548d5ec253
Quelldatensatz
uspto-grants-1984_11
Patentnummer
US04483706

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