Quinolinic Acid → 4,6-Diamino-1,3-benzenediol pyridinedicarboxylate

HRID 1994174

Reaktionsgleichung

Reaktionsgleichung von HRID 1994174
Cl.Cl.[NH2:3][C:4]1[CH:9]=[C:8]([NH2:10])[C:7]([OH:11])=[CH:6][C:5]=1[OH:12].[N:13]1[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([OH:21])=[O:20])[C:14]=1[C:22]([OH:24])=[O:23].N1C=CC=C(C([O-])=O)C=1C([O-])=O.[Na+].[Na+]>O.[OH-].[Na+]>[NH2:3][C:4]1[CH:9]=[C:8]([NH2:10])[C:7]([OH:11])=[CH:6][C:5]=1[OH:12].[N:13]1[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([O-:21])=[O:20])[C:14]=1[C:22]([O-:24])=[O:23]

Komponenten

6

Edukt 3

HCID 1066Quinolinic AcidHCID 27336484,6-Diaminoresorcinol Dihydrochloride2×HCID 13430307Disodium pyridinedicarboxylate

Produkt 1

HCID 866229924,6-Diamino-1,3-benzenediol pyridinedicarboxylate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 14798Sodium HydroxideLösungsmittel

Versuchsvorschrift

7 parts by weight of 4,6-diamino-1,3-benzenediol dihydrochloride was dissolved in 33 parts by weight of water deaerated with nitrogen. 5.347 parts by weight of pyridinedicarboxylic acid was dissolved in 64 parts by weight of 1M sodium hydroxide solution and deaerated with nitrogen. The 4,6-diamino-1,3-benzenediol dihydrochloride solution was added dropwise to the disodium pyridinedicarboxylate solution over 10 minutes to form a white precipitate of 4,6-diamino-1,3-benzenediol/pyridinedicarboxylate. In this case, the reaction temperature was kept at 90° C. The obtained salt was filtered, dispersed and mixed into 3,000 parts by weight of water deaerated with nitrogen, and then filtered again. This dispersion, mixing and filtration operation was repeated three times.

Quellen und Nachweise

ORD-Eintrag
ord-1310b28b3fb84d7aac74fa2ad2af9861
Quelldatensatz
uspto-grants-2010_01
Patentnummer
US07652124B2

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