N-(2-methoxy-4-nitrophenyl)methanesulfonamide → N-(4-amino-2-methoxyphenyl)methanesulfonamide
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([N+:9]([O-])=O)[CH:6]=[CH:5][C:4]=1[NH:12][S:13]([CH3:16])(=[O:15])=[O:14]>CO.[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([NH2:9])[CH:6]=[CH:5][C:4]=1[NH:12][S:13]([CH3:16])(=[O:15])=[O:14]Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
A solution of 2-methoxy-4-nitro-methanesulfonylaminobenzene (1 g) in methanol (20 ml) containing palladium on carbon (10%, 100 mg) was stirred at RT under hydrogen for 48 h. The mixture was filtered through celite then evaporated to give 2-methoxy-4-amino-methanesulfonylaminobenzene as a brown gum. This was used without purification in the following reaction.
Aufarbeitung
- filtrationThe mixture was filtered through celite
- customthen evaporated
Quellen und Nachweise
- ORD-Eintrag
- ord-b1e54b3518a942d8962e71b836721636
- Quelldatensatz
- uspto-grants-2010_06
- Patentnummer
- US07745490B2
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