Acetyl chloride → (2R,5R)-5-[(1S,2S)-2-Acetylamino-3-(3-benzyloxyphenyl)-1-hydroxypropyl]-2-(1-methyl-cyclopentylmethoxy)-morpholine-4-carboxylic acid tert-butyl ester

Reaktionsgleichung

[C:1](Cl)(=[O:3])[CH3:2].[C:5]([O:9][C:10]([N:12]1[C@@H:17]([CH:18]([OH:36])[CH:19]([NH2:35])[CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([O:27][CH2:28][C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)[CH:22]=2)[CH2:16][O:15][C@@H:14]([O:37][CH2:38][C:39]2([CH3:44])[CH2:43][CH2:42][CH2:41][CH2:40]2)[CH2:13]1)=[O:11])([CH3:8])([CH3:7])[CH3:6].C(N(CC)C(C)C)(C)C>ClCCl.C(OCC)(=O)C>[C:5]([O:9][C:10]([N:12]1[C@@H:17]([C@@H:18]([OH:36])[C@@H:19]([NH:35][C:1](=[O:3])[CH3:2])[CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([O:27][CH2:28][C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)[CH:22]=2)[CH2:16][O:15][C@@H:14]([O:37][CH2:38][C:39]2([CH3:44])[CH2:40][CH2:41][CH2:42][CH2:43]2)[CH2:13]1)=[O:11])([CH3:8])([CH3:6])[CH3:7]