4-(Trifluoromethyl)benzaldehyde → 201164-14-9

HRID 2059450Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2059450
O=Cc1ccc(C(F)(F)F)cc1.CON(C)C(=O)CC(=O)O>NCc1ccccc1.O=C(O)C(F)(F)F.CN(C)c1ccncc1.CN(C)C=O>CON(C)C(=O)/C=C/c1ccc(C(F)(F)F)cc1

Komponenten

6

Edukt 2

HCID 679964-(Trifluoromethyl)benzaldehydeHCID 11263568HCID 11263568, Verbindung

Produkt 1

HCID 9449823201164-14-9Ausbeute 71 %

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 142844-(Dimethylamino)pyridineReagenzHCID 12484433Benzenemethanamine, trifluoroacetateKatalysatorHCID 6228DimethylformamideLösungsmittel

Reaktionsbedingungen

Temperatur
50 °C

Aufarbeitung

  1. temperatureThe product mixture was cooled to 25 °C.
  2. filtrationFiltered through a pad of celite · Organic-Phase beibehalten
  3. wash"The celite was washed with ethyl acetate (3 x 1 mL)."
  4. concentrationThe filtrate was concentrated under reduced pressure
  5. additionA 0.07 M stock solution of the internal standard ethylene carbonate (0.70 mL in CDCl3) was added.

Quellen und Nachweise

ORD-Eintrag
ord-983bcc712e8641be92d7f0dabc0d5b50
Quelldatensatz
Transfer learning optimization of 26 decarboxylative olefination reactions

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