(2R,3S,4R,5R,6S)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol → ethyl lauroyl arginine HCL

HRID 2063174

Reaktionsgleichung

Reaktionsgleichung von HRID 2063174
N[C@H](C(O)=O)CCCNC(=N)N.[CH2:13]([N:15]([C:27](=[O:39])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[C@H:16]([C:24]([OH:26])=[O:25])[CH2:17][CH2:18][CH2:19][NH:20][C:21](=[NH:23])[NH2:22])[CH3:14].C(O)[C@@H]1O[C@H](O[C@]2(CCl)O[C@H](C[Cl:54])[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H](O)[C@H]1Cl>O>[ClH:54].[CH2:13]([N:15]([C:27](=[O:39])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[C@H:16]([C:24]([OH:26])=[O:25])[CH2:17][CH2:18][CH2:19][NH:20][C:21](=[NH:22])[NH2:23])[CH3:14]

Komponenten

5

Edukt 3

HCID 70683051(2R,3S,4R,5R,6S)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diolHCID 178418600HCID 178418600, VerbindungHCID 178443291Ethyl lauroyl arginine

Produkt 1

HCID 178443292ethyl lauroyl arginine HCL

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel2×

Versuchsvorschrift

A series of films containing varying amounts of the arginine derivative compound they hydrochloride salt of ethyl lauroyl arginine designated Compositions A, B and C were prepared by using the ingredients listed in Table VI below. In preparing the film, the hydroxyl propylmethylcellulose polymer ingredient (Methocel E5LV) and carrageenan as added at a temperature of 70° C. to 90° C., to half the amount of total deionized water used, and the solution stirred for 20 minutes at a slow speed using IKA Labortechnik Model RW20DZMixer. The remaining amount of water maintained at room temperature (21° C.) was then added and the mixing continued for 40 minutes. To this solution was added the corn starch ingredient (Cerestar Polar Tex Instant 12640) and the mixture stirred for an additional 20 minutes until the starch was completely dispersed and a homogenous mixture was formed. To this mixture was added sucralose and mixed for 10 minutes after which the emulsifier Tween 80 was added and mixed for an additional 5 minutes. Thereafter, flavor was thoroughly mixed for an additional 30 minutes to form a flurry emulsion to which as a final step the hydrochloride salt of ethyl lauroyl arginine HCL (ELAH) dispersed in canola oil was slowly added until evenly dispersed in the film ingredient slurry. The emulsion was then cast on a polyethylene coated paper substrate and dried in a convection oven at 110° C. to form a solid thin (30 to 60 μm thick) film.

Aufarbeitung

  1. additionA series of films containing
  2. customwere prepared
  3. customIn preparing the film
  4. additionwas then added
  5. waitthe mixing continued for 40 minutes
  6. additionwas completely dispersed
  7. customa homogenous mixture was formed
  8. additionwas added
  9. additionmixed for an additional 5 minutes
  10. additionThereafter, flavor was thoroughly mixed for an additional 30 minutes

Quellen und Nachweise

ORD-Eintrag
ord-760241b2d3e44e16a9dbbab89cf4426f
Quelldatensatz
uspto-grants-2012_10
Patentnummer
US08287843B2

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