Reaktionsgleichung
C=C[C:3](=O)[CH2:4][CH2:5][CH3:6].[C:8](Cl)(=O)[CH2:9]CC.[CH:14](C(C=C)=O)=C.[N:20]1([CH:26]=[CH:27][C:28]2[CH:33]=[CH:32][C:31]([C:34]3[CH:39]=[CH:38][C:37]([CH2:40]CCCC)=[CH:36][CH:35]=3)=[CH:30][CH:29]=2)CC[CH2:23][CH2:22][CH2:21]1>>[CH2:40]([C:37]1[CH:36]=[CH:35][C:34]([C:31]2[CH:30]=[CH:29][C:28]([C:27]3[CH:8]=[CH:9][C:21]([CH2:22][CH2:23][CH3:14])=[N:20][CH:26]=3)=[CH:33][CH:32]=2)=[CH:39][CH:38]=1)[CH2:6][CH2:5][CH2:4][CH3:3]Komponenten
5
Versuchsvorschrift
Example 11 is repeated by reacting hex-1-en-3-one (preparable starting from butanoyl chloride analogously to the vinyl ketone in Example 11) and 1-piperidino-2-(4'-pentylbiphenyl-4-yl)ethene (preparable analogously to the preparation of the enamine in Example 11) to give 5-(4'-pentylbiphenyl-4-yl)-2-propylpyridine having SE 178° SB 211° SA 222° I.
Quellen und Nachweise
- ORD-Eintrag
- ord-819764159ce84ba18c8ad3c4d4e277cb
- Quelldatensatz
- uspto-grants-1990_04
- Patentnummer
- US04913837
Verknüpfte Notizen
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