Water → Undecenyl azide

Temperatur

80 °C

To do this, sodium azide (2.781 g, 43 mmol) was dissolved in 170 ml of dimethylformamide (DMF). 5 ml of undecenyl bromide (36 mmol) were added, with stirring, to the reaction medium, which was subsequently heated at 80° C. for 24 hours. The mixture was left to cool to ambient temperature, and then 100 ml of water were added portionwise. An extraction with ethanol (3×100 ml) was subsequently carried out, and the organic phase was then washed with water (3×100 ml) and dried over sodium sulfate (Na2SO4). Finally, the solvent was evaporated off and 2.58 g of undecenyl azide (20.3 mmol; yield 60%) were isolated in the form of a pale yellow-colored transparent oil.

1. waitThe mixture was left
2. temperatureto cool to ambient temperature
3. extractionAn extraction with ethanol (3×100 ml)
4. washthe organic phase was then washed with water (3×100 ml)
5. dry with materialdried over sodium sulfate (Na2SO4)
6. customFinally, the solvent was evaporated off

ORD-Eintrag

ord-59880d494367462ea83af81fb78a9989

Quelldatensatz

uspto-grants-2011_04

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US07919046B2