Water → HCID 23130682, Verbindung

HRID 2080064Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2080064
[H-].[Al+3].[Li+].[H-].[H-].[H-].[C:7]1([NH:13][CH2:14][C:15]2[CH:22]=[CH:21][C:18]([C:19]#[N:20])=[CH:17][CH:16]=2)[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.O>O1CCCC1>[NH2:20][CH2:19][C:18]1[CH:21]=[CH:22][C:15]([CH2:14][NH:13][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:16][CH:17]=1

Komponenten

5

Edukt 3

HCID 962WaterHCID 11148468Benzonitrile, 4-[(phenylamino)methyl]-HCID 21226445Aluminium lithium hydride

Produkt 1

HCID 23130682HCID 23130682, VerbindungAusbeute 97,1 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel2×

Versuchsvorschrift

Next, to a solution of lithium aluminum hydride (0.91 g, 24 mmol) in tetrahydrofuran (60 mL) was added a solution of the resulting 4-phenylaminomethyl-benzonitrile (2.0 g, 9.61 mmol) in tetrahydrofuran (5 mL), and the solution was stirred at room temperature for 2 hours. Water was added to the reaction solution, which was then extracted with ethyl acetate, dried over anhydrous magnesium sulfate, and the solvent was evaporated to obtain the title compound (1.98 g, 97%) as a yellow oil. This compound was used in the next reaction without purification.

Aufarbeitung

  1. extractionwas then extracted with ethyl acetate
  2. dry with materialdried over anhydrous magnesium sulfate
  3. customthe solvent was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-e91aeb5823c2405ead7cad30ca605678
Quelldatensatz
uspto-grants-2011_04
Patentnummer
US07932272B2

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