1-Hydroxybenzotriazole → Tert-butyl 4-(2-((6-(2-cyanophenyl)-2-(3-fluorophenethylamino)nicotinamido)methyl)pyrrolidin-1-yl)-4-oxobutylcarbamate

Reaktionsgleichung

Cl.[C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10]1[CH:24]=[CH:23][C:13]([C:14]([NH:16][CH2:17][CH:18]2[CH2:22][CH2:21][CH2:20][NH:19]2)=[O:15])=[C:12]([NH:25][CH2:26][CH2:27][C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([F:34])[CH:29]=2)[N:11]=1)#[N:3].[C:35]([O:39][C:40]([NH:42][CH2:43][CH2:44][CH2:45][C:46](O)=[O:47])=[O:41])([CH3:38])([CH3:37])[CH3:36].C1C=CC2N(O)N=NC=2C=1.CN(C(ON1N=NC2C=CC=CC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CCN(C(C)C)C(C)C>CN(C=O)C>[C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10]1[CH:24]=[CH:23][C:13]([C:14]([NH:16][CH2:17][CH:18]2[CH2:22][CH2:21][CH2:20][N:19]2[C:46](=[O:47])[CH2:45][CH2:44][CH2:43][NH:42][C:40](=[O:41])[O:39][C:35]([CH3:36])([CH3:38])[CH3:37])=[O:15])=[C:12]([NH:25][CH2:26][CH2:27][C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([F:34])[CH:29]=2)[N:11]=1)#[N:3]