Hydrogen Peroxide → HCID 19780238, Verbindung

HRID 2081586Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2081586
[Cl:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][N:6]=1.[OH:15]O>C(O)(=O)C>[Cl:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][N+:6]=1[O-:15]

Komponenten

4

Edukt 2

HCID 784Hydrogen PeroxideHCID 124351852-[(2-Chlorophenyl)methyl]pyridine

Produkt 1

HCID 19780238HCID 19780238, VerbindungAusbeute 100 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

A solution of 2-(o-chlorobenzyl)pyridine (32 g, 0.16 moles) and hydrogen peroxide (30% w/v, 10.7 g, 36.0 ml, 0.31 moles) in glacial acetic acid (100 ml) was heated at 75° C. for 17 hours. The reaction mixture was cooled to room temperature, the acetic acid evaporated under reduced pressure and the residue dissolved in chloroform. After neutralisation with potassium carbonate (30 g) the chloroform was removed to give 2-(o-chlorobenzyl)pyridine-N-oxide (34.4 g, 100%) as a viscous oil.

Aufarbeitung

  1. customthe acetic acid evaporated under reduced pressure
  2. dissolutionthe residue dissolved in chloroform
  3. customAfter neutralisation with potassium carbonate (30 g) the chloroform was removed

Quellen und Nachweise

ORD-Eintrag
ord-26b07bd79075432c8b440f9728a0dbde
Quelldatensatz
uspto-grants-1993_02
Patentnummer
US05185339

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