Hydrochloric Acid → 4-Biphenylyl benzoate

HRID 2082109Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2082109
[C:1](Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:13][CH:12]=1.Cl.O>N1C=CC=CC=1>[C:1]([O:10][C:11]1[CH:12]=[CH:13][C:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:15][CH:16]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

6

Edukt 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 71034-HydroxybiphenylHCID 7412Benzoyl chloride

Produkt 1

HCID 2317434-Biphenylyl benzoateAusbeute 94 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

128 ml benzoyl chloride is dripped into a solution of 170 g 4-hydroxybiphenyl in 500 ml pyridine, at 20° C.; subsequently, the reaction mixture is heated under reflux for 30 min. After cooling, the reaction mixture is mixed with a solution of 500 ml concentrated hydrochloric acid and 750 ml water. The remaining precipitate is filtered off, washed neutral with water, dried and recrystallized from n-butanol (melting point: 150° C.); yield: 94%.

Aufarbeitung

  1. temperaturesubsequently, the reaction mixture is heated
  2. temperatureunder reflux for 30 min
  3. temperatureAfter cooling
  4. filtrationThe remaining precipitate is filtered off
  5. washwashed neutral with water
  6. customdried
  7. customrecrystallized from n-butanol (melting point: 150° C.)

Quellen und Nachweise

ORD-Eintrag
ord-0c10c08e9eb6412ab234c4568d03deef
Quelldatensatz
uspto-grants-1993_02
Patentnummer
US05187237

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