Cyclohexanone → 2,6-Bis((4-(ethyl(2-hydroxyethyl)amino)phenyl)methylene)cyclohexan-1-one

HRID 2086532

Reaktionsgleichung

Reaktionsgleichung von HRID 2086532
C([O:4][CH2:5][CH2:6][N:7]([CH2:16][CH3:17])[C:8]1[CH:13]=[CH:12][C:11]([CH:14]=O)=[CH:10][CH:9]=1)(=O)C.[C:18]1(=[O:24])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1.[OH-:25].[Na+]>C(O)C>[CH2:16]([N:7]([CH2:6][CH2:5][OH:4])[C:8]1[CH:9]=[CH:10][C:11]([CH:14]=[C:19]2[CH2:20][CH2:21][CH2:22][C:23](=[CH:14][C:11]3[CH:12]=[CH:13][C:8]([N:7]([CH2:6][CH3:5])[CH2:16][CH2:17][OH:25])=[CH:9][CH:10]=3)[C:18]2=[O:24])=[CH:12][CH:13]=1)[CH3:17]

Komponenten

5

Edukt 3

HCID 7967CyclohexanoneHCID 14798Sodium HydroxideHCID 11458991Benzaldehyde, 4-[[2-(acetyloxy)ethyl]ethylamino]-

Produkt 1

HCID 696185902,6-Bis((4-(ethyl(2-hydroxyethyl)amino)phenyl)methylene)cyclohexan-1-oneAusbeute 185,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
50 °C

Versuchsvorschrift

23.5 g of 2-(ethyl(4-formylphenyl)amino)ethyl acetate, 4.91 g of cyclohexanone and 150 ml of ethanol were mixed and to this was added an aqueous solution (25 ml) of 2.2 g of sodium hydroxide while stirring at 50° C. This mixture was further stirred for 5 hours. After cooling to room temperature, a precipitate was filtrated, and washed with a small amount of ethanol and water to obtain 41.5 g of 2,6-bis((4-(ethyl(2-hydroxyethyl)amino)phenyl)methylene)cyclohexan-1-one.

Aufarbeitung

  1. stirringThis mixture was further stirred for 5 hours
  2. temperatureAfter cooling to room temperature
  3. filtrationa precipitate was filtrated
  4. washwashed with a small amount of ethanol and water

Quellen und Nachweise

ORD-Eintrag
ord-3c148860a4c74c1481c444b95592535e
Quelldatensatz
uspto-grants-2004_04
Patentnummer
US06727037B2

Verknüpfte Notizen

Wird geladen…